Gastrointestinal Physiology E-Book

Leonard R. Johnson

Description

Gastrointestinal Physiology, a volume in the Mosby Physiology Monograph Series, explains the fundamentals of gastrointestinal physiology in a clear and concise manner. Ideal for your systems-based curriculum, this fully updated medical textbook provides you with a basic understanding of how the GI system functions in both health and disease.

• Stay current with clear, accurate, and up-to-the-minute coverage of the physiology of the gastrointestinal system focusing on the needs of the student.
• Bridge the gap between normal function and disease with gastrointestinal pathophysiology content throughout the book.
• Master the material more easily with learning objectives at the start of each chapter, overview boxes, key words and concepts, chapter summaries, and physiology review questions at the end of the book.
• Understand complex concepts by examining clear, 2-color diagrams.
• Apply what you've learned to real-life clinical situations with the aid of featured clinical cases with questions and explained answers.

Informations

• Publié par: Mosby
• Date de parution: 27 août 2013
• Nombre de lectures: 0
• EAN13: 9780323172899
• Langue: English
• Poids de l'ouvrage: 7 Mo

Extrait

G a s t r o i n t e s t i n a l
P h y s i o l o g y
EIGHTH EDITION
Leonard R. Johnson, PhD
Thomas A. Gerwin Professor of Physiology, University of Tennessee Health Sciences Center,
Memphis, TennesseeTable of Contents
Cover image
Title page
Series page
Copyright
Preface
Chapter 1: Regulation: Peptides of the Gastrointestinal Tract
General Characteristics
Discovery
Chemistry
Distribution And Release
Actions And Interactions
Candidate Hormones
Neurocrines
Paracrines
Summary
Chapter 2: Regulation: Nerves and Smooth Muscle
Anatomy Of The Autonomic Nervous System
Neurohumoral Regulation Of Gastrointestinal Function
Anatomy Of The Smooth Muscle Cell
Smooth Muscle Contraction
SummaryChapter 3: Swallowing
Chewing
Pharyngeal Phase
Esophageal Peristalsis
Receptive Relaxation Of The Stomach
Summary
Chapter 4: Gastric Emptying
Anatomic Considerations
Contractions Of The Orad Region Of The Stomach
Contractions Of The Caudad Region Of The Stomach
Contractions Of The Gastroduodenal Junction
Contractions Of The Proximal Duodenum
Regulation Of Gastric Emptying
Summary
Chapter 5: Motility of the Small Intestine
Anatomic Considerations
Types Of Contractions
Patterns Of Contractions
Vomiting
Summary
Chapter 6: Motility of the Large Intestine
Anatomic Considerations
Contractions Of The Cecum And Ascending Colon
Contractions Of The Descending And Sigmoid Colon
Motility Of The Rectum And Anal Canal
Control Of Motility
Summary
Chapter 7: Salivary SecretionFunctions Of Saliva
Anatomy And Innervation Of The Salivary Glands
Composition Of Saliva
Regulation Of Salivary Secretion
Summary
Chapter 8: Gastric Secretion
Functional Anatomy
Secretion Of Acid
Origin Of The Electrical Potential Difference
Electrolytes Of Gastric Juice
Stimulants Of Acid Secretion
Stimulation Of Acid Secretion
Inhibition Of Acid Secretion
Pepsin
Mucus
Intrinsic Factor
Growth Of The Mucosa
Summary
Chapter 9: Pancreatic Secretion
Functional Anatomy
Mechanisms Of Fluid And Electrolyte Secretion
Mechanisms Of Enzyme Secretion
Regulation Of Secretion
Cellular Basis For Potentiation
Response To A Meal
Summary
Chapter 10: Bile Secretion and Gallbladder Function
Overview Of The Biliary System
Constituents Of BileBile Secretion
Gallbladder Function
Expulsion Of Bile
Summary
Chapter 11: Digestion and Absorption of Nutrients
Structural-Functional Associations
Digestion
Absorption
Adaptation Of Digestive And Absorptive Processes
Carbohydrate Assimilation
Protein Assimilation
Lipid Assimilation
Vitamins
Summary
Chapter 12: Fluid and Electrolyte Absorption
Bidirectional Fluid Flux
Ionic Content Of Luminal Fluid
Transport Routes And Processes
Mechanism For Water Absorption And Secretion
Intestinal Secretion
Calcium Absorption
Iron Absorption
Summary
Chapter 13: Regulation of Food Intake
Appetite Control
The Nervous System
The Endocrine System
The Gastrointestinal System
SummaryAppendix
IndexSeries page
Look for these other volumes in the Mosby Physiology Monograph Series titles:
Blaustein et al: CELLULAR PHYSIOLOGY AND NEUROPHYSIOLOGY
Cloutier: RESPIRATORY PHYSIOLOGY
Hudnall: HEMATOLOGY
White & Porterfield: ENDOCRINE AND REPRODUCTIVE PHYSIOLOGY
Koeppen & Stanton: RENAL PHYSIOLOGY
Pappano & Weir: CARDIOVASCULAR PHYSIOLOGYCopyright
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GASTROINTESTINAL PHYSIOLOGY    ISBN: 978-0-323-10085-4
Copyright © 2014, 2007 by Mosby, an imprint of Elsevier Inc.
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This book and the individual contributions contained in it are protected under
copyright by the Publisher (other than as may be noted herein).
Notices
Knowledge and best practice in this field are constantly changing. As new
research and experience broaden our understanding, changes in research
methods, professional practices, or medical treatment may become
necessary. Practitioners and researchers must always rely on their own
experience and knowledge in evaluating and using any information,
methods, compounds, or experiments described herein. In using such
information or methods they should be mindful of their own safety and
the safety of others, including parties for whom they have a professional
responsibility. With respect to any drug or pharmaceutical products
identified, readers are advised to check the most current information
provided (i) on procedures featured or (ii) by the manufacturer of each
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responsibility of practitioners, relying on their own experience and
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Library of Congress Cataloging-in-Publication Data
Johnson, Leonard R., 1942- author.
Gastrointestinal physiology / Leonard R. Johnson. —Eighth edition.
p. ; cm. —(Mosby physiology monograph series)
Preceded by Gastrointestinal physiology / edited by Leonard R. Johnson. 7th ed.
c2007.
Includes bibliographical references and index.
ISBN 978-0-323-10085-4 (pbk.)
I. Title. II. Series: Mosby physiology monograph series.
[DNLM: 1. Digestive System Physiological Phenomena. WI 102]
QP145
612.3—dc23    2013016769
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Printed in China
Last digit is the print number: 9 8 7 6 5 4 3 2 1Preface
The first edition of Gastrointestinal Physiology appeared in 1977. I t developed as a
result of the authors’ teaching experiences and the need for a book on gastrointestinal
physiology wri en and designed for medical students and beginning graduate
students. This eighth edition is directed to the same audience. A s with any new
edition, I believe that it is significantly be er than the previous one. A ll chapters
contain considerable amounts of new material and have been brought up-to-date with
current information, without introducing undue amounts of controversy to confuse
students. N ew figures have been added, others updated, and some chapters
significantly rewritten.
Major changes in this edition are the addition of a list of “Objectives” at the
beginning of chapters and “Clinical A pplications” boxes within chapters. Hopefully
the learning objectives will provide a guide to the important concepts and be an aid to
understanding them. The material presented as clinical applications is meant to
emphasize the significance of some of the basic science, provide some perspective,
and increase student interest.
I am grateful to my own students for pointing out ways to improve the book.
N umerous colleagues in other medical schools and professional institutions have
added their suggestions and criticisms as well. I am thankful for their interest and
help, and I hope that anyone having criticisms of this edition or suggestions for
improving future editions will transmit them to me.
This is the first edition appearing under sole authorship. I n all previous editions,
the motility chapters were wri en by D r. N orman W. Weisbrodt, who has since
retired. I am grateful to him for allowing me to use his material as I saw fit.
I would like to thank H.J . Ehrlein and Michael S chemann for generously allowing
us to link the videos referenced in Chapters 4 and 5, which appear on the website of
the Technische Universität München (
h p://www.wzw.tum.de/humanbiology/data/motility/34/?alt=english). The
videofluoroscopy on gastrointestinal motility of dogs, pigs, and sheep was performed
during the scientific studies of H.J . Ehrlein and his colleagues over a period of 25
years. This video project was supported by an