Hematology, An Issue of Veterinary Clinics: Small Animal Practice

Joanne B. Messick

Description

Current, important information on hematology for all small animal practitioners! Topics will include in-clinic automated hematology analyzers, quality control recommendations for point-of-care hematology analyzers, bone marrow aspiration and biopsy: indications, technique and evaluation, coombs testing and its diagnostic significance, principles and application of flow cytometry and cell sorting, hemolytic anemia due to erythrocyte enzymes deficiencies, role of hepcidin in iron metabolism and potential therapeutic applications, molecular diagnostic testing to identify hematologic malignancies, BCR-ABL in CML, a signaling pathway of initiation and transformation with potentials for targeted therapy, understanding the cause and consequences of neutropenia, hematologic abnormalities in the companion animal cancer patient, neutrophil function testing and application, application of thromboelastography to detect and monitor coagulopathies, evaluation and clinical application of platelet function testing, pathogenesis and most useful test for diagnosing and monitoring disseminated intravascular coagulation, and more!

Sujets

• Smal Animal
• Veterinary Medicine
• Medical
• Médecine

Informations

• Publié par: Saunders
• Date de parution: 28 janvier 2012
• Nombre de lectures: 2
• EAN13: 9781455743247
• Langue: English
• Poids de l'ouvrage: 2 Mo

Extrait

Veterinary Clinics of North America: Small Animal Practice , Vol. 42, No. 1, January 2012
ISSN: 0195-5616
doi: 10.1016/S0195-5616(11)00210-5

Contributors
GUEST EDITOR

JOANNE B. MESSICK, VMD, PhD , Diplomate, American College of Veterinary Pathologists; Associate Professor, Department of Comparative Pathobiology, Purdue University, School of Veterinary Medicine, West Lafayette, Indiana
AUTHORS

ANNE C. AVERY, VMD, PhD , Associate Professor and Director, Clinical Immunology Laboratory, Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado

ANNE M. BARGER, DVM, MS , Diplomate, American College of Veterinary Pathologists; Clinical Associate Professor, Department of Pathobiology, College of Veterinary Medicine, University of Illinois, Urbana, Illinois

MARY K. BOUDREAUX, DVM, PhD , Professor, Department of Pathobiology, Auburn University College of Veterinary Medicine, Auburn, Alabama

MICHAEL O. CHILDRESS, DVM, MS , Diplomate, American College of Veterinary Internal Medicine (Oncology); Assistant Professor of Comparative Oncology, Department of Veterinary Clinical Sciences, Purdue University School of Veterinary Medicine, West Lafayette, Indiana

PETE W. CHRISTOPHERSON, DVM, PhD , Diplomate, American College of Veterinary Pathologists; Assistant Professor, Department of Pathobiology, Auburn University College of Veterinary Medicine, Auburn, Alabama

BENTE FLATLAND, DVM , Diplomate, American College of Veterinary Internal Medicine; Diplomate, American College of Veterinary Pathologists; Assistant Professor of Clinical Pathology, Department of Biomedical and Diagnostic Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, Tennessee

MICHAEL M. FRY, DVM, MS , Diplomate, American College of Veterinary Pathologists (Clinical Pathology), Associate Professor, Department of Biomedical and Diagnostic Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, Tennessee

LUCA GIORI, DVM , Resident, Clinical Pathology, Department of Veterinary Pathology, Hygiene and Health, Università degli Studi di Milano, Milano, Italy

CAROLYN N. GRIMES, DVM , Resident, Clinical Pathology, Department of Biomedical and Diagnostic Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, Tennessee

JOHN W. HARVEY, DVM, PhD , Diplomate, American College of Veterinary Pathologists; Professor of Clinical Pathology and Executive Associate Dean, College of Veterinary Medicine, University of Florida, Gainesville, Florida

SHANNON JONES HOSTETTER, DVM, PhD , Diplomate, American College of Veterinary Pathologists; Assistant Professor, Department of Veterinary Pathology, College of Veterinary Medicine, Iowa State University, Ames, Iowa

JOANNE B. MESSICK, VMD, PhD , Diplomate, American College of Veterinary Pathologists; Associate Professor, Department of Comparative Pathobiology, Purdue University, School of Veterinary Medicine, West Lafayette, Indiana

JENNIFER L. OWEN, DVM, PhD , Clinical Pathology Resident, Department of Physiological Sciences, University of Florida College of Veterinary Medicine, Gainesville, Florida

ROSE E. RASKIN, DVM, PhD , Diplomate, American College of Veterinary Pathologists; Department of Comparative Pathobiology, Purdue University, School of Veterinary Medicine, West Lafayette, Indiana

AMY N. SCHNELLE, DVM , Veterinary Resident in Clinical Pathology, Department of Pathobiology, College of Veterinary Medicine, University of Illinois, Urbana, Illinois

ELIZABETH A. SPANGLER, DVM, PhD , Diplomate, American College of Veterinary Internal Medicine; Diplomate, American College of Veterinary Pathologists; Associate Professor, Department of Pathobiology, Auburn University College of Veterinary Medicine, Auburn, Alabama

TRACY STOKOL, BVSc, PhD , Diplomate, American College of Veterinary Pathologists (Clinical Pathology); Associate Professor, Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York

LINDA M. VAP, MT, DVM , Diplomate, American College of Veterinary Pathologists; Instructor, Department of Microbiology, Immunology, and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, Colorado

K. JANE WARDROP, DVM, MS , Diplomate, American College of Veterinary Pathologists; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, Washington

ELIZABETH G. WELLES, DVM, PhD , Diplomate, American College of Veterinary Pathologists; Professor, Department of Pathobiology, Auburn University, Auburn, Alabama

MELINDA J. WILKERSON, DVM, MS, PhD , Associate Professor, Diagnostic Medicine/Pathobiology, Director of Clinical Immunology and Flow Cytometry Laboratory, College of Veterinary Medicine, Kansas State University, Manhattan, Kansas
Veterinary Clinics of North America: Small Animal Practice
Hematology
Dr. Joanne B. Messick, VMD, PhD
Department of Comparative Pathobiology, Purdue University, School of Veterinary Medicine, 725 Harrison Street, West Lafayette, IN 47907, USA
ISSN  0195-5616
Volume 42 • Number 1 • January 2012

Contents

Contributors
Forthcoming Issues
Hematology
Automated In-Clinic Hematology Instruments for Small Animal Practitioners: What is Available, What Can They Really Do, and How Do I Make a Choice?
Quality Management Recommendations for Automated and Manual In-House Hematology of Domestic Animals
Bone Marrow Cytologic and Histologic Biopsies: Indications, Technique, and Evaluation
Coombs' Testing and Its Diagnostic Significance in Dogs and Cats
Principles and Applications of Flow Cytometry and Cell Sorting in Companion Animal Medicine
Hemolytic Anemia in Dogs and Cats Due to Erythrocyte Enzyme Deficiencies
Role of Hepcidin in Iron Metabolism and Potential Clinical Applications
Molecular Diagnostics of Hematologic Malignancies in Small Animals
Neutropenia in Dogs and Cats: Causes and Consequences
Hematologic Abnormalities in the Small Animal Cancer Patient
Neutrophil Function in Small Animals
Evaluation and Clinical Application of Platelet Function Testing in Small Animal Practice
Laboratory Diagnosis of Disseminated Intravascular Coagulation in Dogs and Cats: The Past, the Present, and the Future
Index
Veterinary Clinics of North America: Small Animal Practice , Vol. 42, No. 1, January 2012
ISSN: 0195-5616
doi: 10.1016/S0195-5616(11)00212-9

FORTHCOMING ISSUES

March 2012
Small Animal Toxicology
Stephen B. Hooser, DVM, PhD and
Safdar A. Khan, DVM, MS, PhD,
Guest Editors
May 2012
Small Animal Theriogenology
Catherine Lamm, DVM, MRCVS, and
Chelsea Makloski, DVM,
Guest Editors
July 2012
Geriatrics
William D. Fortney, DVM,
Guest Editor
RECENT ISSUES
November 2011
Companion Animal Medicine: Evolving Infectious, Toxicological, and Parasitic Diseases
Sanjay Kapil, DVM, MS, PhD,
Guest Editor
September 2011
Surgical Complications
Christopher A. Adin, DVM,
Guest Editor
July 2011
Organ Failure in Critical Illness
Timothy B. Hackett, DVM, MS,
Guest Editor

RELATED INTEREST
Veterinary Clinics of North America: Exotic Animal Practice
January 2009 (Vol. 12, No. 1)
Cardiology
J. Jill Heatley, DVM, MS, Dipl. ABVP–Avian, Dipl. ACZM,
Guest Editor
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Veterinary Clinics of North America: Small Animal Practice , Vol. 42, No. 1, January 2012
ISSN: 0195-5616
doi: 10.1016/j.cvsm.2011.11.002

Preface
Hematology

Joanne B. Messick, VMD, PhD [e-mail] ,
Department of Comparative Pathobiology, Purdue University, School of Veterinary Medicine, 725 Harrison Street, West Lafayette, IN 47907, USA


Joanne B. Messick, VMD, PhD Guest Editor
As the standard of care changes in veterinary medicine, as novel technologies and treatment options develop, we are challenged to keep pace and understand the many advances. This is particularly true of veterinary hematology and is the impetus for this edition. We begin our hematology issue of Veterinary Clinics of North America: Small Animal Practice with a discussion of the newest and most widely used in-clinic hematology analyzers. These bench top systems are often smaller versions of large capacity laboratory analyzers providing blood cell counts with red cell indices and either a five- or a three-part white cell differential. Equally important is the inclusion of a complementary article that provides information and suggestions for using these systems and for providing reliable hematology results. These two articles as well as those related to Coombs' testing, understanding the causes and consequences of neutropenia, and diagnosis and monitoring disseminated intravascular coagulation provide an overview as well as information about more recent studies and advances related to these topics. Major hematologic abnormalities that may be identified in small animal cancer patients, including increases or decreases in the numbers of circulating blood cells, coagulopathies, and plasma protein dyscrasias, are also reviewed. There is clearly a need for future studies addressing the risk and clinical significance of these, and perhaps other, hematologi