Intravascular Physiology, An Issue of Interventional Cardiology Clinics
99 pages
English

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99 pages
English

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Description

This issue of Interventional Cardiology Clinics, edited by Allen Jeremias, is devoted to Intravascular Physiology. Dr. Jeremias assembled a group of expert contributors to review the following topics: Evolution of Coronary Physiology – Basic Concepts of FFR and CFR; Concept of "Functional PCI" – The Rational for Physiologic Lesion Assessment for PCI Guidance; Limitations and Pitfalls of FFR and Adenosine-Induced Hyperemia; Evidence for the Use of FFR to Guide Clinical Decision-Making – The Landmark FFR Clinical Trials; Evaluation of Microvascular Disease and Clinical Outcomes; Hyperemic vs. Resting Indices for the Assessment of CAD; FFR for the Evaluation of Tandem and Bifurcations Lesions, Left Main, and Acute Coronary Syndromes; and CT-FFR: Basic Concept and Clinical Implementation.

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Publié par
Date de parution 07 janvier 2016
Nombre de lectures 0
EAN13 9780323400916
Langue English
Poids de l'ouvrage 2 Mo

Informations légales : prix de location à la page 0,5242€. Cette information est donnée uniquement à titre indicatif conformément à la législation en vigueur.

Extrait

Intravascular Physiology
Interventional Cardiology Clinics
Editor
Allen Jeremias, MD, MSc
Division of Cardiovascular Medicine, Department of Medicine, Health Sciences Center, Stony Brook, NY, USA
Editor-in-Chief
Matthew J. Price

Clinics Review Articles

www.interventional.theclinics.com

October 2015 Volume 4 Number 4
Table of Contents
Cover image
Title page
Copyright
Contributors
Editor-in-Chief
Editor
Authors
Forthcoming Issues
Forthcoming Issues
Recent Issues
Preface. Coronary Physiology: Basic Concepts and Clinical Applications
History and Development of Coronary Flow Reserve and Fractional Flow Reserve for Clinical Applications
Key points
Introduction
Clinical motivations
Technical developments
Coronary flow reserve
Fractional flow reserve
Summary
Financial support and relationships with industry
References
The Concept of Functional Percutaneous Coronary Intervention: Why Physiologic Lesion Assessment Is Integral to Coronary Angiography
Key points
Introduction
Appropriate use criteria for coronary revascularization
Noninvasive ischemic evaluation
Anatomic lesion severity and coronary hemodynamics
Invasive evaluation of ischemia
Fractional flow reserve as an integral part of coronary angiography
A new approach of functional angiography
Summary
References
Limitations and Pitfalls of Fractional Flow Reserve Measurements and Adenosine-Induced Hyperemia
Key points
Introduction
Basic principles and prerequisites
Pitfalls of fractional flow reserve measurements
Limitations of methods for induction of hyperemia
Limitations of a single cutoff value
Summary
References
Landmark Fractional Flow Reserve Trials
Key points
Introduction
Validation in comparison to noninvasive ischemia assessment
Safety of revascularization deferral with normal fractional flow reserve in single-vessel coronary disease
Fractional-flow-reserve-guided revascularization in multivessel disease
Fractional-flow-reserve-guided revascularization among patients with stable coronary disease
Summary/discussion
References
Evaluation of Microvascular Disease and Clinical Outcomes
Key points
Introduction
Direct angiographic assessment
Coronary flow reserve
Resting coronary flow patterns
Index of microcirculatory resistance
Instantaneous hyperemic diastolic velocity-pressure slope
Wave intensity analysis
Summary
References
Can Resting Indices Obviate the Need for Hyperemia and Promote the Routine Use of Physiologically Guided Revascularization?
Key points
Introduction
Is hyperemia physiologically essential for the pressure-only assessment of a stenosis?
Is hyperemia essential to unmask true stenosis severity?
Is hyperemia useful in vessels with tandem stenoses?
Future areas for development
Summary
Acknowledgments
References
Fractional Flow Reserve for the Evaluation of Tandem and Bifurcation Lesions, Left Main, and Acute Coronary Syndromes
Key points
Introduction
Fractional flow reserve in tandem lesions
Fractional flow reserve in ostial or bifurcation lesions
Fractional flow reserve in left main coronary artery disease
Fractional flow reserve in acute coronary syndromes
Summary
References
Noninvasive Fractional Flow Reserve Derived from Coronary Computed Tomography Angiography for the Diagnosis of Lesion-specific Ischemia
Key points
Introduction
Fractional flow reserve for the assessment of lesion-specific ischemia
Noninvasive fractional flow reserve computed from standard coronary computed tomography angiography images
Evidence in the literature on the diagnostic value of FFR CT
Cost-effectiveness of FFR CT
Future perspectives
Summary
References
Association of Wall Shear Stress with Coronary Plaque Progression and Transformation
Key points
Introduction
Role of wall shear stress in endothelial function
Mechanotransduction of wall shear stress in endothelial cells
Effects of wall shear stress on the endothelium
Role of wall shear stress in coronary plaque progression
Coronary plaque transformation
Summary
References
Copyright
ELSEVIER
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INTERVENTIONAL CARDIOLOGY CLINICS Volume 4, Number 4
October 2015 ISSN 2211-7458, ISBN-13: 978-0-323-40090-9
Editor: Adrianne Brigido
Developmental Editor: Barbara Cohen-Kligerman
2015 Elsevier Inc. All rights reserved.
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Printed in the United States of America.
Contributors
Editor-in-Chief
MATTHEW J. PRICE, MD , Assistant Professor, Scripps Translational Science Institute; Director of the Cardiac Catheterization Laboratory, Scripps Green Hospital, La Jolla, California
Editor
ALLEN JEREMIAS, MD, MSc, FACC , Division of Cardiovascular Medicine, Department of Medicine, Stony Brook University Medical Center, Stony Brook, New York
Authors
SUNG GYUN AHN, MD, PhD , Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, Georgia; Division of Cardiology, Yonsei University, Wonju College of Medicine, Yonsei University, Seoul, Korea
LOHENDRAN BASKARAN, MD , Department of Radiology, Dalio Institute of Cardiovascular Imaging, New York-Presbyterian Hospital, Weill Cornell Medical College, New York, New York
ADAM J. BROWN, MD , Department of Cardiovascular Medicine, University of Cambridge, Cambridge, United Kingdom
CHRISTOPHER J. BROYD, PhD, MBBS , Cardiovascular Institute, Hospital Cl nico San Carlos, Madrid, Spain
ENRICO CERRATO, MD , Cardiovascular Institute, Hospital Cl nico San Carlos, Madrid, Spain
IBRAHIM DANAD, MD , Department of Radiology, Dalio Institute of Cardiovascular Imaging, New York-Presbyterian Hospital, Weill Cornell Medical College, New York, New York
JUSTIN DAVIES, BSc, MBBS, MRCP, PhD , Consultant Cardiologist and Senior Lecturer, International Centre for Circulatory Health, N

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