Medical Sciences E-Book

Jeannette Naish, Denise Syndercombe Court

Description

An integrated approach to teaching basic sciences and clinical medicine has meant that medical students have been driven to a range of basic science textbooks to find relevant information. Medical Sciences is designed to do the integration for you. In just one book, the diverse branches of medical science are synthesised into the appropriate systems of the human body, making this an invaluable aid to approaching the basics of medicine within in a clinical context.

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An integrated approach to teaching basic sciences and clinical medicine has meant that medical students have been driven to a range of basic science textbooks to find relevant information. Medical Sciences does the integration for you. In just one book, the diverse branches of medical science are synthesised into the appropriate systems of the human body, making this an invaluable aid to approaching the basics of medicine within in a clinical context.

• Eleven new contributors.
• Completely new chapters on Biochemistry and cell biology, Genetics, The nervous system, Bones, muscle and skin, Endocrine and reproductive systems, The cardiovascular system, The renal system and Diet and nutrition.
• Completely revised and updated throughout with over 35 new illustrations .
• Expanded embryology sections with several new illustrations.

Informations

• Publié par: Saunders Ltd.
• Date de parution: 02 mai 2014
• Nombre de lectures: 1
• EAN13: 9780702052491
• Langue: English
• Poids de l'ouvrage: 10 Mo

Extrait

Medical Sciences
Second Edition
Jeannette Naish, MBBS MSc FRCGP
Clinical Senior Lecturer, Wolfson Institute of Preventive Medicine, Barts and The London School of Medicine and Dentistry, London, UK
Denise Syndercombe Court, CBiol MSB CSci FIBMS DMedT MFSoc PhD
Honorary Research Fellow, Queen Mary University of London
Reader in Forensic Genetics, King's College London, London, UK
Table of Contents
Cover image
Title page
Dedication
Copyright
Contributors
Preface
Acknowledgements
1: Introduction and homeostasis
CHAPTER 2 BIOCHEMISTRY AND CELL BIOLOGY
CHAPTER 3 ENERGY METABOLISM
CHAPTER 4 PHARMACOLOGY
CHAPTER 5 HUMAN GENETICS
CHAPTER 6 PATHOLOGY AND IMMUNOLOGY
CHAPTER 7 EPIDEMIOLOGY
SYSTEMS OF THE BODY
CHAPTER 16 DIET AND NUTRITION
HOMEOSTASIS
2: Biochemistry and cell biology
PRINCIPLES OF MOLECULAR INTERACTIONS
CHEMICAL COMPOSITION OF THE HUMAN BODY
THE CELL
3: Energy metabolism
INTRODUCTION TO METABOLISM
CARBOHYDRATE METABOLISM
AMINO ACID METABOLISM
LIPID METABOLISM (Clinical box 3.19)
4: Pharmacology
INTRODUCTION
PHARMACOKINETICS
PHARMACODYNAMICS
Adenylate cyclase and cAMP
Guanylate cyclase, cGMP and nitric oxide (NO)
Phosphodiesterase inhibition
Nitric oxide
Inositol phosphates
DAG
THE AUTONOMIC NERVOUS SYSTEM
5: Human genetics
INTRODUCTION
THE HUMAN GENOME
HUMAN GENETIC VARIATION
MODES OF INHERITANCE
POLYGENIC OR COMPLEX DISEASE
CANCER GENETICS
IDENTIFYING DISEASE GENES
GENETIC DISEASE, DIAGNOSIS AND THERAPY
6: Pathology and immunology
INTRODUCTION
INFECTION
IMMUNITY
NEOPLASIA
7: Epidemiology: science for the art of medicine
INTRODUCTION
THE EPIDEMIOLOGICAL APPROACH
EPIDEMIOLOGICAL ENQUIRY
INVESTIGATION BY REVIEW
HEALTH EDUCATION AND PROMOTION
8: The nervous system
INTRODUCTION
EMBRYOLOGY
GROSS ANATOMY
THE VENTRICULAR SYSTEM
CELLS OF THE NERVOUS SYSTEM
BLOOD SUPPLY TO THE BRAIN AND BRAIN METABOLISM
TRANSMISSION OF NEURAL SIGNALS
MOTOR CONTROL AND PATHWAYS
SENSORY SYSTEMS
SPECIAL SENSES
CENTRAL AUTONOMIC NETWORKS
CONSCIOUSNESS
SLEEP AND WAKEFULNESS
EMOTION
MOTIVATION AND GOAL-DIRECTED BEHAVIOURS
HIGHER CORTICAL FUNCTIONS
BRAIN DEATH
9: Bone, muscle, skin and connective tissue
INTRODUCTION
THE SKELETAL SYSTEM
JOINTS
SKELETAL MUSCLE
POSTURE AND LOCOMOTION
SPECIALISED CONNECTIVE TISSUES: SKIN, HAIR AND NAILS
GENERALISED CONNECTIVE TISSUE
10: Endocrinology
INTRODUCTION
THE ENDOCRINE SYSTEM
NEUROENDOCRINOLOGY
ENDOCRINE HOMEOSTASIS
REPRODUCTIVE PHYSIOLOGY
11: The cardiovascular system
INTRODUCTION
CLINICAL ANATOMY OF THE CARDIOVASCULAR SYSTEM
EMBRYOLOGY
CELLULAR STRUCTURE AND FUNCTION OF THE HEART
BLOOD VESSELS
SYSTEMIC ARTERIAL BLOOD PRESSURE
12: Haematology
THE HAEMOPOIETIC SYSTEM
RED CELLS
ONCOGENESIS AND DISORDERS OF BLOOD CELL PRODUCTION
HAEMOSTASIS AND THROMBOSIS
BLOOD GROUPS AND TRANSFUSION MEDICINE
13: The respiratory system
INTRODUCTION
EPIDEMIOLOGY OF RESPIRATORY DISEASE AND ITS SOCIAL IMPACT
CLASSIFICATION OF COMMON RESPIRATORY DISEASES
ANATOMY OF THE RESPIRATORY SYSTEM
MECHANICS OF BREATHING
PRINCIPLES OF GAS EXCHANGE
CARRIAGE OF OXYGEN BY THE BLOOD
CARRIAGE OF CARBON DIOXIDE BY THE BLOOD
MATCHING LUNG VENTILATION TO LUNG PERFUSION
CONTROL OF BREATHING
ENERGY PRODUCTION AND OXYGEN CONSUMPTION
CHALLENGES TO NORMAL RESPIRATION
RESPIRATORY FAILURE
LUNG DEFENCES AGAINST INFECTION
DEVELOPMENT OF THE LUNGS AND CHANGES IN THE NEWBORN
14: The renal system
INTRODUCTION
ANATOMY OF THE KIDNEY
DEVELOPMENT OF THE KIDNEY
RENAL FUNCTION
THE URINARY TRACT
RENAL DISEASES
15: The alimentary system
INTRODUCTION
OVERVIEW OF DIGESTION AND ABSORPTION
SURFACE ANATOMY OF THE ABDOMEN
MICROANATOMY OF THE GASTROINTESTINAL TRACT
MOUTH
SALIVARY GLANDS
PHARYNX AND OESOPHAGUS
STOMACH AND DUODENUM
CONTROL OF GASTRIC SECRETIONS
GASTRIC MOTILITY
EXOCRINE PANCREAS
THE LIVER AND BILIARY SYSTEM
SMALL INTESTINE
LARGE INTESTINE
16: Diet and nutrition
INTRODUCTION
DIET
NUTRITIONAL STATUS
MICRONUTRIENTS AND WATER
THE CONTROL OF FOOD INTAKE
Index
Dedication
We would like to dedicate this book to all medical students, past and future, and to all future doctors. You have to know the science in order to understand the practice of medicine.
Jeannette Naish
Denise Syndercombe Court
Copyright

© 2015 Elsevier Ltd. All rights reserved.
No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permission in writing from the publisher. Details on how to seek permission, further information about the Publisher’s permissions policies and our arrangements with organizations such as the Copyright Clearance Center and the Copyright Licensing Agency, can be found at our website: www.elsevier.com/permissions .
This book and the individual contributions contained in it are protected under copyright by the Publisher (other than as may be noted herein).
First edition 2009
Second edition 2015
ISBN 9780702051388
British Library Cataloguing in Publication Data
A catalogue record for this book is available from the British Library
Library of Congress Cataloging in Publication Data
A catalog record for this book is available from the Library of Congress

Notices
Knowledge and best practice in this field are constantly changing. As new research and experience broaden our understanding, changes in research methods, professional practices, or medical treatment may become necessary.
Practitioners and researchers must always rely on their own experience and knowledge in evaluating and using any information, methods, compounds, or experiments described herein. In using such information or methods they should be mindful of their own safety and the safety of others, including parties for whom they have a professional responsibility.
With respect to any drug or pharmaceutical products identified, readers are advised to check the most current information provided (i) on procedures featured or (ii) by the manufacturer of each product to be administered, to verify the recommended dose or formula, the method and duration of administration, and contraindications. It is the responsibility of practitioners, relying on their own experience and knowledge of their patients, to make diagnoses, to determine dosages and the best treatment for each individual patient, and to take all appropriate safety precautions.
To the fullest extent of the law, neither the Publisher nor the authors, contributors, or editors, assume any liability for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions, or ideas contained in the material herein.



Printed in China
Contributors
Andrew Archbold, MD FRCP , Consultant Cardiologist, Barts Health NHS Trust, London Chest Hospital, London, UK
Alistair Chesser, MB BChir FRCP PhD , Consultant Nephrologist, Barts Health NHS Trust, The Royal London Hospital, Whitechapel, London, UK
Marek H. Dominiczak, dr hab med FRCPath FRCP (Glas)
Honorary Professor of Clinical Biochemistry and Medical Humanities, University of Glasgow
Consultant Biochemist, NHS Greater Glasgow and Clyde, Department of Biochemistry, Gartnavel General Hospital, Glasgow, UK
Paola Domizio, BSc MBBS FRCPath
Professor of Pathology Education, Institute of Cell and Molecular Science, Barts and the London School of Medicine and Dentistry, Queen Mary University of London
Department of Cellular Pathology, Barts Health NHS Trust, The Royal London Hospital, Whitechapel, London, UK
Gavin Donaldson, BSc PhD , Reader in Respiratory Medicine, National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, UK
Joy Hinson, BSc PhD DSc FHEA , Professor of Endocrine Science, Dean for Postgraduate Studies, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, UK
Mark Holness, BSc PhD , Reader in Diabetes and Metabolism, Institute of Cell and Molecular Science, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, UK
David P. Kelsell, BSc PhD , Professor of Human Molecular Genetics, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, UK
Jeannette Naish, MBBS MSc FRCGP , Clinical Senior Lecturer, Wolfson Institute of Preventive Medicine, Barts and The London School of Medicine and Dentistry, London, UK
Girish Namagondlu, MBBS, MRCP , Consultant Nephrologist, Barts Health NHS Trust, Royal London Hospital, Whitechapel, London, UK
Penny Neild, MD FRCP , Consultant Gastroenterologist and Honorary Senior Lecturer, St George’s Hospital, St. George’s University of London, London, UK
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