Multiple Sclerosis 3, Volume 34 E-Book

Claudia Lucchinetti, Reinhard Hohlfeld

Description

Multiple Sclerosis 3 emphasizes the latest in the pharmacologic treatment of this incurable inflammatory demyelinating disorder. Primary editors Claudia Lucchinetti, MD, and Reinhard Hohlfeld, MD, with the aid of all new contributors, present a complete and current reference on multiple sclerosis that includes discussions of such hot topics as Biomarkers, Genomics, and Surrogate Outcomes in MS; Pediatric MS; Transverse Myelitis; Attack Therapies in MS; Current Disease-Modifying Therapeutic Strategies in MS; Management of Aggressive MS; Symptomatic Therapies in MS; Complementary and Alternative Medical Therapies; and Strategies to Promote Neuroprotection and Repair. Distinguish between MS and other similar demyelinating disorders and know the best and most aggressive methods of treatment. This title in the Blue Books of Neurology series is exactly what you need to treat the disease and its relapses.

• Covers the latest clinical advances and relevant discussions—Biomarkers, Genomics, and Surrogate Outcomes in MS; Pediatric MS; Transverse Myelitis; Attack Therapies in MS; Current Disease-Modifying Therapeutic Strategies in MS; Management of Aggressive MS; Symptomatic Therapies in MS; Complementary and Alternative Medical Therapies; and Strategies to Promote Neuroprotection and Repair—to bring you up to date and keep your practice state-of-the-art.
• Features a greater emphasis on practical management to help you determine the type of multiple sclerosis and the best course of therapy.
• Focuses on pharmaceutical therapies so you know the best and most aggressive methods and which drugs to use for treatment.
• Includes extensive information on differential diagnosis so that you can clearly distinguish between multiple sclerosis and other similar demyelinating disorders.
• Presents expert new editors and experienced contributing authors for the most current and relevant practice information.
• Emphasizes the pharmacologic management of patients with multiple sclerosis to address treating the actual disease and its relapses as well as treating the symptoms.

Informations

• Publié par: Saunders
• Date de parution: 29 octobre 2009
• Nombre de lectures: 0
• EAN13: 9781437711295
• Langue: English
• Poids de l'ouvrage: 3 Mo

Extrait

Blue Books of Neurology
Multiple Sclerosis 3
Claudia F. Lucchinetti, MD *
Reinhard Hohlfeld, MD *
Professor of Neurology, Chair, Division of Multiple Sclerosis and Autoimmune Neurology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
Professor and Director, Institute for Clinical Neuroimmunlogy, Klinikum Grosshadern, Ludwig Maximilians University, Munich, Germany
ISSN  1877-184X
Volume 35 • Suppl. C • 2010

Contents
Cover
Copyright
Blue books of Neurology
Contributing authors
Series Preface
Preface
Chapter 1: Clinical Features and Natural History of Multiple Sclerosis: The Nature of the Beast
Chapter 2: Differential Diagnosis and Diagnostic Criteria for Multiple Sclerosis: Application and Pitfalls
Chapter 3: Uncovering the Genetic Architecture of Multiple Sclerosis
Chapter 4: Epidemiology of Multiple Sclerosis: Environmental Factors
Chapter 5: Advances in Multiple Sclerosis Imaging
Chapter 6: Biomarkers in Multiple Sclerosis
Chapter 7: Cognitive and Psychiatric Disorders in Multiple Sclerosis
Chapter 8: Gender Issues and Multiple Sclerosis
Chapter 9: Pediatric Multiple Sclerosis
Chapter 10: Clinically Isolated Syndromes
Chapter 11: Acute Disseminated Encephalomyelitis
Chapter 12: Transverse Myelitis: Pathogenesis, Diagnosis, and Management
Chapter 13: Neuromyelitis Optica
Chapter 14: Attack Therapies in Multiple Sclerosis
Chapter 15: Current Disease-Modifying Therapeutic Strategies in Multiple Sclerosis
Chapter 16: Management of Aggressive Multiple Sclerosis: Options and Challenges
Chapter 17: Symptomatic Therapy in Multiple Sclerosis
Chapter 18: Unconventional Medicine and Multiple Sclerosis: The Role of Conventional Health Providers
Chapter 19: Is Multiple Sclerosis a Neurodegenerative Disorder?
Chapter 20: Lessons from the Past and Future Approaches for Immunologic Therapies in Multiple Sclerosis
Chapter 21: Strategies to Promote Neuroprotection and Repair in Multiple Sclerosis
Index
Blue Books of Neurology , Vol. 35, Suppl. C, 2010
ISSN: 1877-184X
doi: 10.1016/B978-1-4160-6068-0.00022-X

Copyright
SAUNDERS
ELSEVIER
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Philadelphia, PA 19103-2899
MULTIPLE SCLEROSIS 3 ISBN: 978-1-4160-6068-0
Copyright © 2010 by Saunders, an imprint of Elsevier Inc.
All rights reserved. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or any information storage and retrieval system, without permission in writing from the publisher.
Permissions may be sought directly from Elsevier’s Health Sciences Rights Department in Philadelphia, PA, USA: phone: [phone], fax: [phone], e-mail: [e-mail] . You may also complete your request on-line via the Elsevier homepage ( http://www.elsevier.com ), by selecting ‘Customer Support’ and then ‘Obtaining Permissions’.

Notice
Knowledge and best practice in this field are constantly changing. As new research and experience broaden our knowledge, changes in practice, treatment, and drug therapy may become necessary or appropriate. Readers are advised to check the most current information provided (i) on procedures featured or (ii) by the manufacturer of each product to be administered, to verify the recommended dose or formula, the method and duration of administration, and contraindications. It is the responsibility of the practitioner, relying on his or her own experience and knowledge of the patient, to make diagnoses, to determine dosages and the best treatment for each individual patient, and to take all appropriate safety precautions. To the fullest extent of the law, neither the publisher nor the editors assume any liability for any injury and/or damage to persons or property arising out of or related to any use of the material contained in this book.
The Publisher
Library of Congress Cataloging-in-Publication Data
Multiple sclerosis 3 / [edited by] Claudia F. Lucchinetti, Reinhard Hohlfeld. — 1st ed.
p. cm. — (Blue books of neurology series; 35)
Includes bibliographical references and index.
ISBN 978-1-4160-6068-0 (alk. paper)
1. Multiple sclerosis. I. Lucchinetti, Claudia F. II. Hohlfeld, R. (Reinhard) III. Title: Multiple sclerosis three. IV. Series: Blue books of neurology; 35.
[DNLM: 1. Multiple Sclerosis. W1 BU9749 v.35 2009 / WL 360 M96256 2009]
RC377.M8394 2009
616.8′34—dc22 2009007831
ISBN-13: 978-1-4160-6068-0
Acquisitions Editor: Adrianne Brigido
Developmental Editor: John Ingram
Project Manager: Hemamalini Rajendrababu
Design Direction: Steve Stave
Printed in China
Last digit is the print number: 9 8 7 6 5 4 3 2 1
Blue Books of Neurology , Vol. 35, Suppl. C, 2010
ISSN: 1877-184X
doi: 10.1016/B978-1-4160-6068-0.00023-1

BLUE BOOKS OF NEUROLOGY

1 Clinical Neurophysiology
ERIC STALBERG • ROBERT R. YOUNG
2 Movement Disorders
C. DAVID MARSDEN • STANLEY FAHN
3 Cerebral Vascular Disease
MICHAEL J.G. HARRISON • MARK L. DYKEN
4 Peripheral Nerve Disorders
ARTHUR K. ASBURY • R.W. GILLIATT
5 The Epilepsies
ROGER J. PORTER • PAOLO I. MORSELLI
6 Multiple Sclerosis
W. IAN McDONALD • DONALD H. SILBERBERG
7 Movement Disorders 2
C. DAVID MARSDEN • STANLEY FAHN
8 Infections of the Nervous System
PETER G.E. KENNEDY • RICHARD T. JOHNSON
9 The Molecular Biology of Neurological Disease
ROGER N. ROSENBERG • ANITA E. HARDING
10 Pain Syndromes in Neurology
HOWARD L. FIELDS
11 Principles and Practice of Restorative Neurology
ROBERT R. YOUNG • PAUL J. DELWAIDE
12 Stroke: Populations, Cohorts, and Clinical Trials
JACK P. WHISNANT
13 Movement Disorders 3
C. DAVID MARSDEN • STANLEY FAHN
14 Mitochondrial Disorders in Neurology
A.H.V. SCHAPIRA • SALVATORE DIMAURO
15 Peripheral Nerve Disorders 2
ARTHUR K. ASBURY • P.K. THOMAS
16 Contemporary Behavioral Neurology
MICHAEL R. TRIMBLE • JEFFREY L. CUMMINGS
17 Headache
PETER J. GOADSBY • STEPHEN D. SILBERSTEIN
18 The Epilepsies 2
ROGER J. PORTER • DAVID CHADWICK
19 The Dementias
JOHN H. GROWDON • MARTIN N. ROSSOR
20 Hospitalist Neurology
MARTIN A. SAMUELS
21 Neurologic Complications in Organ Transplant Recipients
EELCO F.M. WIJDICKS
22 Critical Care Neurology
DAVID H. MILLER • ERIC C. RAPS
23 Neurology of Bladder, Bowel, and Sexual Dysfunction
CLARE J. FOWLER
24 Muscle Diseases
ANTHONY H.V. SCHAPIRA • ROBERT C. GRIGGS
25 Clinical Trials in Neurologic Practice
JOSE BILLER • JULIEN BOGOUSSLAVSKY
26 Mitochondrial Disorders in Neurology 2
A.H.V. SCHAPIRA • SALVATORE DIMAURO
27 Multiple Sclerosis 2
W. IAN McDONALD • JOHN H. NOSEWORTHY
28 Motor Neuron Disorders
PAMELA J. SHAW • MICHAEL J. STRONG
29 Prevention and Treatment of Ischemic Stroke
SCOTT E. KASNER • PHILIP B. GORELICK
30 The Dementias 2
JOHN H. GROWDON • MARTIN N. ROSSOR
31 Spinocerebellar Degenerations: The Ataxias and Spastic Paraplegias
ALEXIS BRICE • STEFAN-M. PULST
32 Neuro-Ophthalmology
DESMOND P. KIDD • NANCY J. NEWMAN • VALERIE BIOUSSE
33 The Epilepsies 3
SIMON SHORVON • TIMOTHY A. PEDLEY
34 Multiple Sclerosis 3
CLAUDIA F. LUCCHINETTI • REINHARD HOHLFELD
35 Movement Disorders 4
ANTHONY H.V. SCHAPIRA • ANTHONY E.T. LANG • STANLEY FAHN
Blue Books of Neurology , Vol. 35, Suppl. C, 2010
ISSN: 1877-184X
doi: 10.1016/B978-1-4160-6068-0.00024-3

CONTRIBUTING AUTHORS

Nuhad E. Abou Zeid, MD,
Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minnesota

Alberto Ascherio, MD, DrPH
Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts

Brenda Banwell, MD
Associate Professor of Paediatrics (Neurology), Director, Pediatric Multiple Sclerosis Program, The Hospital for Sick Children, Toronto, Ontario, Canada

Angela Bates, MD
Fellow, Department of Neurology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas

Tamir Ben-Hur, MD, Phd
Professor and Head, Department of Neurology, The Agnes Ginges Center for Human Neurogenetics, Hadassah–Hebrew University Medical Center, Jerusalem, Israel

Allen C. Bowling, MD, PhD
Medical Director, Multiple Sclerosis Service, Colorado Neurological Institute, Clinical Associate Professor of Neurology, University of Colorado–Denver and Health Sciences Center, Englewood, Colorado

Scott L. Davis, PhD
Assistant Professor, Department of Neurology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas

Philip L. De Jager, MD
Instructor, Department of Neurology, Harvard Medical School, Division of Molecular Immunology, Center for Neurologic Diseases, Brigham & Women’s Hospital, Boston, Massachusetts, Program in Medical and Population Genetics, Broad Institute of Harvard University and Massachusetts Ins