Obesity

Manuel Serrano Ríos, J. M. Ordovas, Jose A. Gutiérrez Fuentes

Description

• Obesity is the second volume in a four-title series, along with Type 2 Diabetes Mellitus (T2D), Arterial Hypertension, and Atherogenic dyslipidemia.
• It covers every major aspect of obesity from a multidisciplinary approach, thanks to collaborative efforts of a select team of international, world-reknowned experts.
• It offers updated information on a wide variety of topics, ranging from the general to the specific. These include the pathophysiology of obesity; the influence of social, demographic and economic factors, as well as the importance of genetics; the connection between obesity and diabetes; prevention strategies; obesity in children and its impact on the Public Health System; treatment options, both pharmacological and psychological, and the importance of physical activity.

• Obesity is the second volume in a four-title series, along with Type 2 Diabetes Mellitus (T2D), Arterial Hypertension, and Atherogenic dyslipidemia.
• It covers every major aspect of obesity from a multidisciplinary approach.
• It offers updated information on a wide variety of topics, ranging from the general to the specific. These include the pathophysiology of obesity; the influence of social, demographic and economic factors, etc.

Sujets

• Médecine
• Spécialités médicales
• Medical
• Metabolism
• Endocrinology

Informations

• Publié par: Elsevier
• Date de parution: 07 février 2011
• Nombre de lectures: 0
• EAN13: 9788480865364
• Langue: English

Extrait

Table of Contents

Cover image
Front Matter
Copyright
Contributors
Preface
Chapter 1. Leptin and the regulation of body weight
Chapter 2. Obesity: A Modern Pandemic
Chapter 3. Developmental origins of childhood obesity: Potential public health impact
Chapter 4. Genetics of Obesity: Are Genetic Differences Contributing to the Obesity Epidemic?
Chapter 5. Social, Demographic, and Economic Status Factors and Obesity: A Global Perspective
Chapter 6. The adipose tissue: From a passive fat depot to an active endocrine organ
Chapter 7. Endocrine Regulation of Energy Homeostasis: Implications for Obesity and Diabetes
Chapter 8. Gene-Diet Interactions and Obesity
Chapter 9. Neuroendocrine Regulation of Food Intake and Body Weight
Chapter 10. Obesity, Inflammation and the Metabolic Syndrome
Chapter 11. Obesity and the Liver. Pathophysiological Implications
Chapter 12. Fat Tissue and Cardiovascular Diseases. The Fat Connection
Chapter 13. Obesity and Type 2 Diabetes Mellitus. The reciprocal impact
Chapter 14. Fat tissue, Thrombosis and Atherosclerosis
Chapter 15. Current Guidelines on the Identification, Evaluation, and Treatment of Overweight and Obesity
Chapter 16. Prevention of Child and Adolescent Overweight and Obesity
Chapter 17. The Role of Physical Activity and Sedentary Behavior on Obesity
Chapter 18. Obesity treatment: The use of exercise and behavioral strategies
Chapter 19. Lifestyle Approaches to Obesity Treatment
Chapter 20. Pharmacological Approaches in Obesity Treatment
Chapter 21. Surgical Treatment of Obesity
Chapter 22. Caloric Restriction and Aging
Glossary
Index
Front Matter
Obesity

Obesity
EDITORS
Manuel Serrano-Ríos
Department of Medicine, School of Medicine, Complutense University. Madrid, Spain
José M. Ordovás
Nutrition and Genomics Laboratory, USDA Human Nutrition Research Center on Aging at Tufts University. Boston, Massachusetts, USA
José A. Gutiérrez-Fuentes
Fundación Lilly. Madrid, Spain

Ámsterdam Barcelona Beijing Boston Filadelfia Londres Madrid
México Milán Múnich Orlando París Roma Sídney Tokio Toronto
Copyright

© 2010 Elsevier España, S.L.
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ISBN: 978-84-8086-740-5
Depósito legal: B. 596-2010
Producción editorial: Gea Consultoría Editorial, s.l.
Impreso en España por Gráficas 92 S.A.

Advertencia
La medicina es un área en constante evolución. Aunque deben seguirse unas precauciones de seguridad estándar, a medida que aumenten nuestros conocimientos gracias a la investigación básica y clínica habrá que introducir cambios en los tratamientos y en los fármacos. En consecuencia, se recomienda a los lectores que analicen los últimos datos aportados por los fabricantes sobre cada fármaco para comprobar las dosis recomendadas, la vía y duración de la administración y las contraindicaciones. Es responsabilidad ineludible del médico determinar las dosis y el tratamiento más indicados para cada paciente, en función de su experiencia y del conocimiento de cada caso concreto. Ni los editores ni los directores asumen responsabilidad alguna por los daños que pudieran generarse a personas o propiedades como consecuencia del contenido de esta obra.
El Editor
Contributors
Angelo Avogaro
Department of Clinical and Experimental Medicine, University of Padova School of Medicine. Padova, Italy
Lina Badimón
Centro de Investigación Cardiovascular - CSIC/ICCC. Hospital de la Santa Creu i Sant Pau. Barcelona, Spain
CIBER OBN , Instituto de Salud Carlos III. Madrid , Spain
Cátedra de Investigación Cardiovascular, (UAB-HSCSP-Fundación Jesús Serra). Barcelona. Spain
Tom Baranowski
US Department of Agriculture, Agricultural Research Service Children's Nutrition Research Center. Houston, Texas, USA
Department of Pediatrics, Baylor College of Medicine. Houston, Texas, USA
Claude Bouchard
Pennington Biomedical Research Center of Louisiana State University. Baton Rouge, Louisiana, USA
George A Bray
Division of Clinical Obesity and Metabolism
Pennington Biomedical Research Center of Louisiana State University. Baton Rouge, Louisiana, USA
Andrew A. Bremer
Department of Pediatrics, School of Medicine, University of California. Davis, California, USA
Kelliann Davis
Department of Health and Physical Activity, Physical Activity and Weight Management Research Center, University of Pittsburgh. Pittsburgh, Pennsylvania, USA
Ulf Ekelund
MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital. Cambridge, UK
Jeffrey M. Friedman
Laboratory of Molecular Genetics, The Rockefeller University. New York, USA
Gema Frühbeck
Metabolic Research Laboratory, Clínica Universitaria, University of Navarra. Pamplona, Spain
Luc F. van Gaal
Department of Diabetology, Metabolism and Clinical Nutrition, Antwerp University Hospital. Antwerp, Belgium
Jessica Gokee-LaRose
Psychiatry & Human Behavior, Brown Medical School/The Miriam Hospital. Providence, Rhode Island, USA
Peter J. Havel
Department of Nutrition, University of California. Davis, California, USA
Meredith A. Hawkins
Department of Medicine, Albert Einstein College of Medicine. Bronx, New York, USA
Rodrigo Hernández Vera
Centro de Investigación Cardiovascular, CSIC-ICCC, Hospital de la Santa Creu i Sant Pau. Barcelona, Spain
CIBER OBN , Instituto de Salud Carlos III. Madrid, Spain
Tamas L. Horvath
Department of Neurobiology, Section of Comparative Medicine, BBS Program, Yale University School of Medicine. New Haven, Connecticut, USA
John M. Jakicic
Department of Health and Physical Activity, Physical Activity and Weight Management Research Center, University of Pittsburgh. Pittsburgh, Pennsylvania, USA
Philip T. James
International Obesity Task Force. London, UK
Nicole Larson
Division of Epidemiology and Community Health, University of Minnesota. Minneapolis, Minnesota, USA
Erik Näslund
Department of Clinical Sciences, Danderyds Hospital, Karolinska Institute. Stockholm, Sweden
Amy D. Otto
Department of Health and Physical Activity, Physical Activity and Weight Management Research Center, University of Pittsburgh. Pittsburgh, Pennsylvania, USA
Eric Ravussin
Division of Health and Performance Enhancement Human Physiology, Exercise Laboratory, Pennington Biomedical Research Center. Louisiana State University. Baton Rouge, Louisiana, USA
Leanne M. Redman
Pennington Biomedical Research Center, Louisiana State University. Baton Rouge, Louisiana, USA
Jamie Stang
Division of Epidemiology and Community Health, University of Minnesota. Minneapolis, Minnesota, USA
Mary Story
Division of Epidemiology and Community Health, University of Minnesota. Minneapolis, Minnesota, USA
Gemma Vilahur
Centro de Investigación Cardiovascular, CSIC-ICCC, Hospital de la Santa Creu i Sant Pau. Barcelona, Spain
CIBER OBN , Instituto de Salud Carlos III. Madrid, Spain
Youfa Wang
Center for Human Nutrition, Department of International Health, Johns Hopkins Bloomberg School of Public Health
Baltimore, Maryland, USA
Rena R. Wing
Psychiatry and Human Behavior, Brown Medical School/The Miriam Hospital. Providence, Rhode Island, USA
Jianping Ye
Antioxidant and Gene Regulation Lab, Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, Louisiana, USA
Hannele Yki-Järvinen
Department of Medicine, Division of Diabetes, University of Helsinki. Helsinki, Finland
Preface
Obesity is a common, serious and growing problem. Epidemiological evidence indicates that 1.1 billion people worldwide are above their ideal weight. In the US, 66.7% of adults are overweight or obese, but despite these appalling numbers, the continental US ranks “only” third among the top ten Fattest Countries in the World. The first position goes to American Samoa with 93.5% of the population being overweight/obese. Interestingly, these top ten countries do not seem to follow any specific geographical, cultural, ethnic or economic clustering, and include populations as diverse as Germans (number 4, 66.5%); Egyptians (number 5, 66%); New Zealand people (number 7, 62.7%); Croatians (number 9, 61.4%) and finally the English that closes the list with 61%. In the US alone, obesity is blamed as a contributing factor in over 300,000 deaths annually, with economic costs reaching more than US$ 100 billion. In view of this, public health authorities have declared that we are suffering a pandemic of “ globesity ”, term coined by the World Health Organization in 2001 to impress upon us the widespread enormity of the problem. However, the most worrisome aspect of this pandemic is not in its current prevalence but in the forecasted trends for the next few decades, especially knowing that currently, children and adolescents are the segment of the population with the fastest growing overweight and obesity rates. The prediction models from the UK Foresight Report (Tackling Obesities: Future Choices —Modelling Future Trends in Obesity and the Impact on Health) indicate that, in the UK, by 2050, 60% of males and 50% of females could be obese. But this model does not account for the number of o