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522 pages

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Apply a systematic pattern recognition method to achieve more accurate diagnoses with Practical Breast Pathology: A Diagnostic Approach. Using a practical, pattern-based organization, this volume in the Pattern Recognition series guides you efficiently and confidently through the evaluation of even the most challenging neoplastic and non-neoplastic specimens in breast pathology, and also highlights patterns crucial to radiologic diagnosis.

  • Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located.

  • Compare specimens to commonly seen patterns, categorize them accordingly, and turn directly to in-depth diagnostic guidance using the unique, pattern-based Visual Index at the beginning of the book.

  • Assess key pathologic and clinical aspects of both neoplastic and non-neoplastic conditions with over 530 high-quality, full-color images that help you evaluate and interpret biopsy samples.

  • Apply the latest techniques and advances in the field, including optimal processing of breast specimens for early detection of breast cancer, the latest molecular diagnosis in breast pathology, and the use of radiology in optimizing detection of breast lesions.
  • Progress logically from the histological pattern, through the appropriate work-up, around the pitfalls, and to the best diagnosis.
  • Find the information you’re looking for quickly and easily with patterns color-coded to specific entities in the table of context and text and key points summarized in tables, charts, and graphs.
  • Review all the information essential for completing a sign-out report: clinical findings, pathologic findings, diagnosis, treatment, and prognosis.
  • View key diagnostic features associated with less common conditions in a visual encyclopedia of unusual patterns at the end of the book.



Publié par
Date de parution 29 octobre 2012
Nombre de lectures 0
EAN13 9781455733408
Langue English
Poids de l'ouvrage 7 Mo

Informations légales : prix de location à la page 0,0744€. Cette information est donnée uniquement à titre indicatif conformément à la législation en vigueur.


Practical Breast Pathology
A Diagnostic Approach

Kristen A. Atkins, MD
Associate Professor, Director, Residency Program, Department of Pathology, University of Virginia, Charlottesville, Virginia

Christina S. Kong, MD
Associate Professor, Director, Cytopathology Service, Director, Cytopathology Fellowship, Department of Pathology, Stanford University School of Medicine, Stanford, California
Table of Contents
Cover image
Title page
Series page
Series Preface
Patterns-Based Approach to Diagnosis
Chapter 1: The Normal Breast
Normal Gross Anatomy
Normal Histology
Secondary Changes
Differential Diagnosis
Ancillary Studies
Chapter 2: Specimen Processing
Fine Needle Aspiration Biopsy
Needle Core Biopsies
Excisional Biopsy
Margin Specimens
Reexcision Specimens
Reduction Mammoplasty
Lymph Nodes
Chapter 3: Basic Breast Radiology
Imaging Evaluation of Patients
Breast Imaging Reporting and Data System
Imaging Characteristics
Biopsy Techniques: Image-Guided Biopsy Methods
Differential Diagnosis
Management after Biopsy
Chapter 4: Surgical Approaches to Breast Lesions
Fine Needle Aspiration Biopsy
Core Needle Biopsy
Fine Needle Aspiration or Core Needle Biopsy of Presumed Axillary Lymph Node
Excisional Biopsy
Surgery after Neoadjuvant Therapy
Sentinel Lymph Node Biopsy
Axillary Dissection
Mesenchymal Lesions
Chapter 5: Juvenile Breast Lesions
Normal Growth and Development
Congenital and Developmental Abnormalities
Endocrine Disorders
Infectious/Inflammatory Lesions
Stroma-Predominant Tumors and Tumor-like Lesions
Fibroepithelial Tumors
Benign Epithelial-Predominant Tumors
Malignant Tumors
Chapter 6: Fibrosing Lesions of the Breast
Fibrocystic Changes
Sclerosing Adenosis
Sclerosing Lymphocytic Lobulitis
Pseudoangiomatous Stromal Hyperplasia
Radial Scar
Fat Necrosis
Chapter 7: Stromal Lesions/Sarcomas (Including Mixed Epithelial/Stromal, Metaplastic [Spindle Cell] Carcinoma, and Vascular)
Phyllodes Tumor
Mammary Myofibroblastoma
Pseudoangiomatous Stromal Hyperplasia
Metaplastic Carcinoma (Spindle Cell/Sarcomatoid Carcinoma)
Primary Sarcoma Other Than Angiosarcoma
Chapter 8: Intraductal and Intralobular Proliferations
Usual Ductal Hyperplasia
Columnar Cell Lesions
Atypical Ductal Hyperplasia
Atypical Lobular Hyperplasia
Lobular Carcinoma In Situ
Ductal Carcinoma In Situ
Apocrine Lesions
Papillary Lesions
Chapter 9: Invasive Breast Carcinomas
Invasive Ductal Carcinoma, Not Otherwise Specified
Invasive Lobular Carcinoma
Tubular Carcinoma
Tubulolobular Carcinoma
Invasive Cribriform Carcinoma
Invasive Papillary Carcinoma
Invasive Micropapillary Carcinoma
Adenoid Cystic Carcinoma
Medullary Carcinoma
Neuroendocrine Carcinoma
Mucin-Producing Carcinoma
Apocrine Carcinoma
Inflammatory Carcinoma
Secretory Carcinoma
Chapter 10: Cutaneous Lesions of the Breast
Benign Melanocytic Lesions
Atypical Melanocytic Lesions
Paget Disease of the Breast
Cutaneous Involvement of Breast Cancer
Benign Adnexal Tumors
Malignant Adnexal Tumors
Atypical Vascular Lesions
Radiation Dermatitis
Silicone Mastitis
Chapter 11: Sentinel Lymph Nodes
Sentinel Lymph Node Biopsy
Macrometastatic Carcinoma
Micrometastatic Carcinoma
Isolated Tumor Cell Clusters
Chapter 12: Fine Needle Aspiration Cytology
Fibrocystic Change
Lactational Change
Papillary Neoplasm
Post-therapeutic Changes
Chapter 13: Special Studies
Prognostic and Predictive Markers
Myoepithelial Markers
Lymphovascular Markers
Epithelial Markers
Markers of Ductal versus Lobular Differentiation
Markers of Breast Differentiation
Gene Expression Profiling
Series page
Pattern Recognition Series
Series editors: Kevin O. Leslie and Mark R. Wick
Practical Breast Pathology
Edited by Kristen A. Atkins and Christina S. Kong
Practical Cytopathology
Edited by Matthew Zarka and Barbara Centeno
Practical Dermatopathology
Written by James W. Patterson
Practical Hepatic Pathology
Edited by Romil Saxena
Practical Pulmonary Pathology, Second Edition
Edited by Kevin O. Leslie and Mark R. Wick
Practical Renal Pathology
Edited by Donna J. Lager and Neil A. Abrahams
Practical Soft Tissue Pathology
Edited by Jason L. Hornick
Practical Surgical Neuropathology
Edited by Arie Perry and Daniel J. Brat

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Copyright © 2013 by Saunders, an imprint of Elsevier Inc.
All rights reserved. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Details on how to seek permission, further information about the Publisher’s permissions policies and our arrangements with organizations such as the Copyright Clearance Center and the Copyright Licensing Agency, can be found at our website: .
This book and the individual contributions contained in it are protected under copyright by the Publisher (other than as may be noted herein).

Knowledge and best practice in this field are constantly changing. As new research and experience broaden our understanding, changes in research methods, professional practices, or medical treatment may become necessary.
Practitioners and researchers must always rely on their own experience and knowledge in evaluating and using any information, methods, compounds, or experiments described herein. In using such information or methods they should be mindful of their own safety and the safety of others, including parties for whom they have a professional responsibility.
With respect to any drug or pharmaceutical products identified, readers are advised to check the most current information provided (i) on procedures featured or (ii) by the manufacturer of each product to be administered, to verify the recommended dose or formula, the method and duration of administration, and contraindications. It is the responsibility of practitioners, relying on their own experience and knowledge of their patients, to make diagnoses, to determine dosages and the best treatment for each individual patient, and to take all appropriate safety precautions.
To the fullest extent of the law, neither the Publisher nor the authors, contributors, or editors, assume any liability for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions, or ideas contained in the material herein.
Library of Congress Cataloging-in-Publication Data
Practical breast pathology : a diagnostic approach / [edited by] Kristen A. Atkins, Christina S. Kong.
p. ; cm.—(Pattern recognition series)
Includes bibliographical references and index.
ISBN 978-1-4377-0763-2 (hardcover : alk. paper)
I. Atkins, Kristen A. II. Kong, Christina S. III. Series: Pattern recognition series.
[DNLM: 1. Breast Diseases. 2. Breast—pathology. WP 840]
Acquistions Editor: William R. Schmitt
Publishing Services Manager: Pat Joiner-Myers
Project Manager: Marlene Weeks
Designer: Lou Forgione
Printed in China.
Last digit is the print number: 9 8 7 6 5 4 3 2 1
This book is dedicated to my husband, Jason, my kids, Cole and Renee, and my parents, Pope and Joan, for their endless support and humor. It is also in honor of my aunts and my best friend who are closer to the subject matter than anyone cares to be, and to the memory of my mother-in-law. And of course to my co-editor, Christina, my far away buddy.

Kristen A. Atkins
To my father for all he has taught me.

Christina S. Kong

Kristen A. Atkins, MD
Associate Professor Director, Residency Program Department of Pathology University of Virginia Charlottesville, Virginia

Catherine Barry, DO
Attending Pathologist Department of Pathology and Laboratory Medicine Cedars-Sinai Medical Center Los Angeles, California

Gerald J. Berry, MD
Professor Department of Pathology Director, Surgical Pathology Fellowship Stanford University School of Medicine Stanford, California

David R. Brenin, MD
Chief, Breast Surgical Services Co-Director, University of Virginia Breast Center Department of Surgery University of Virginia Health Center Charlottesville, Virginia

Yunn-Yi Chen, MD, PhD
Professor Director, Immunoh

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