Primary Immunodeficiency Disorders, An Issue of Immunology and Allergy Clinics of North America 35-4

Anthony Montanaro

Description

This issue of Immunology and Allergy Clinics of North America, Guest Edited by Anthony Montanaro, MD, is devoted to Primary Immunodeficiency Disorders. Dr. Montanaro has assembled a group of expert authors to review the following topics: Overview of Immunodeficiency Disorder; Severe Combined Immunodeficiency Disorder; Specific Antibody Deficiencies; Common Variable Immunodeficiency; Pulmonary Manifestations of Primary Immunodeficiency Disorders; Approach to the Child with Recurrent Infections; Immunoglobulin Treatment for Primary Immunodeficiency; Bone Marrow Transplantation for Primary Immunodeficiency; and Autoimmune Manifestations of Primary Immunodeficiency.

Sujets

• Médecine
• Médecine Générale
• Medical
• Immunology

Informations

• Publié par: Elsevier
• Date de parution: 07 janvier 2016
• Nombre de lectures: 0
• EAN13: 9780323413350
• Langue: English
• Poids de l'ouvrage: 3 Mo

Extrait

Primary Immunodeficiency Disorders
Immunology and Allergy Clinics of North America
Editor
Anthony Montanaro, MD
Division of Allergy and Immunology, Oregon Health and Sciences University, Portland, OR, USA

www.immunology.theclinics.com

Clinics Review Articles

November 2015 Volume 35 Number 4
Table of Contents
Cover image
Title page
Copyright
Contributors
Editor
Authors
Forthcoming Issues
Forthcoming Issues
Recent Issues
Preface. Primary Immunodeficiency Disorders
Overview of Immunodeficiency Disorders
Key points
Introduction
History
Epidemiology
Classification
Disorders of immune dysregulation
Autoinflammatory disorders
Phenocopies of primary immunodeficiency disorders
Diagnosis
History and physical examination
Laboratory investigations
Treatment
Prognosis
Future of the study of primary immunodeficiency disorders
References
Approach to Children with Recurrent Infections
Key points
Introduction
Symptoms/Signs
Diagnostic test/imaging study
Differential diagnosis
Treatment
Management
Summary
References
Common Variable Immunodeficiency: Diagnosis, Management, and Treatment
Key points
Introduction
Diagnosis
Epidemiology
Pathogenesis
Management
Concluding remarks
References
Specific Antibody Deficiencies
Key points
Introduction
Pathophysiology
Epidemiology
Natural history
Symptoms
Diagnostic evaluation
Management
Prognosis
Future considerations
Summary
References
Severe Combined Immunodeficiency Disorders
Key points
Introduction
Future considerations/summary
References
Hematopoietic Stem Cell Transplant for Immune Deficiency and Immune Dysregulation Disorders
Key points
Introduction
Important points to consider when contemplating hematopoietic stem cell transplant for primary immunodeficiency disorder
Stem cell donor selection
Conditioning regimen
Graft-versus-host disease and prophylaxis
Graft failure
Donor chimerism
Summary
References
Immunoglobulin Replacement Therapy for Primary Immunodeficiency
Key points
Introduction
Clinical applications
Dosage
Routes of administration
Patient monitoring
Adverse effects
Summary
Acknowledgments
References
Autoimmune Disease in Primary Immunodeficiency: At the Crossroads of Anti-Infective Immunity and Self-Tolerance
Key points
Introduction
Defective tolerance in primary immunodeficiencies
Autoimmune and inflammatory complications of common variable immunodeficiency
Summary
References
Pulmonary Manifestations of Primary Immunodeficiency Disorders
Key points
Introduction
Pulmonary infectious complications of primary immunodeficiency disorder
Noninfectious complications of primary immunodeficiency disorder
Obstructive airway disease and bronchiectasis
Parenchymal/interstitial lung disease in primary immunodeficiency disorder
Malignancy
Autoimmunity in primary immunodeficiency disorder
Screening and testing recommendations
Other points
Summary
References
Primary Immunodeficiency Masquerading as Allergic Disease
Key points
Introduction
All that itches is not always eczema
Primary immune deficiency presenting with newborn and infant eczema
PIDs presenting with eosinophilia, increased immunoglobulin E, and eczema: it may not just be atopy
Summary
References
Copyright
ELSEVIER
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IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA Volume 35, Number 4
November 2015 ISSN 0889-8561, ISBN-13: 978-0-323-41334-3
Editor: Jessica McCool
Developmental Editor: Kristen Helm
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Contributors
Editor
ANTHONY MONTANARO, MD
Chief, Division of Allergy and Immunology, Oregon Health and Science University, Portland, Oregon
Authors
JORDAN K. ABBOTT, MA, MD
Division of Allergy and Immunology, Department of Pediatrics, National Jewish Health, Denver, Colorado
MARK BALLOW, MD
Professor, Division of Allergy and Immunology, Department of Pediatrics, University of South Florida, Saint Petersburg, Florida
LAURI BURROUGHS, MD
Seattle Children's Hospital; Assistant Professor, Pediatrics, Bone Marrow Transplant, University of Washington School of Medicine; Director, Non-Malignant Transplant Program, Fred Hutchinson Cancer Research Center, Seattle, Washington
SANNY K. CHAN, MD, PhD
Assistant Professor, Division of Allergy and Immunology, Department of Pediatrics, National Jewish Health, Denver, Colorado
IVAN K. CHINN, MD
Assistant Professor of Pediatrics, Section of Immunology, Allergy, and Rheumatology, Department of Pediatrics, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas
VICTORIA R. DIMITRIADES, MD
Assistant Professor, Section of Allergy Immunology, Department of Pediatrics, Louisiana State University Health Sciences Center, Jeffrey Modell Center for Primary Immunodeficiencies, New Orleans, Louisiana
CHITRA DINAKAR, MD
Division of Allergy, Asthma and Immunology, Department of Pediatrics, Children s Mercy Hospital, University of Missouri-Kansas City, Kansas City, Missouri
ERWIN W. GELFAND, MD
Professor, Division of Allergy and Immunology, Department of Pediatrics, National Jewish Health, Denver, Colorado
DAVID HAGIN, MD, PhD
Senior Fellow, Allergy/Immunology, Seattle Children s Hospital; University of Washington School of Medicine; Seattle Children's Research Institute, Seattle, Washington
VIVIAN P. HERNANDEZ-TRUJILLO, MD
Director, Division of Al