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Quickly learn the microbiology fundamentals you need to know with Medical Microbiology, 7th Edition, by Dr. Patrick R. Murray, Dr. Ken S. Rosenthal, and Dr. Michael A. Pfaller. Newly reorganized to correspond with integrated curricula and changing study habits, this practical and manageable text is clearly written and easy to use, presenting clinically relevant information about microbes and their diseases in a succinct and engaging manner.

  • Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located.
  • Master the essentials of medical microbiology, including basic principles, immunology, laboratory diagnosis, bacteriology, virology, mycology, and parasitology.
  • Progress logically through consistently formatted chapters that examine etiology, epidemiology, disease presentation, host defenses, identification, diagnosis, prevention, and control for each microbe.
  • Grasp complex material quickly with summary tables and text boxes that emphasize essential concepts and issues.
  • Learn the most up-to-date and relevant information in medical microbiology.
  • Study efficiently thanks to a reorganized format that places review chapters at the beginning of each section and review questions at the end of each chapter.
  • Focus on clinical relevance with new interactive case presentations to introduce each of the microbial pathogens that illustrate the epidemiology, diagnosis, and treatment of infectious diseases.
  • Visualize the clinical presentations of infections with new and updated clinical photographs, images, and illustrations.

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Publié par

Date de parution

29 octobre 2012

Nombre de lectures

14

EAN13

9780323091244

Langue

English

Poids de l'ouvrage

7 Mo

Virus Copyright Salmonella Hantavirus Flavivirus Enterobacteriaceae DNA Typhus Listeria Neisseria gonorrhoeae Chlamydia trachomatis Vibrio cholerae Clostridium Mycobacterium tuberculosis Mite Anthrax Campylobacter Cytokine RNA Polysaccharide Trematoda Cestoda Bacillus anthracis Pseudomonas Toxoplasma gondii Helicobacter pylori Rickettsia Vibrio Fasciola hepatica Vaccine City Rhabdoviridae Orthomyxoviridae Poxviridae Candida Prion Brucella Legionella pneumophila Borrelia Toxin Chlamydophila Mycoplasma Haemophilus influenzae Helicobacter Clostridium perfringens Aspergillus Bunyaviridae Togaviridae Corynebacterium Interféron Bartonella Pseudomonas aeruginosa Legionella Treponema Aeromonas Parasites Alphavirus Neisseria Gene Streptococcus pyogenes Rabies Antibodies Plague Papillomavirus In Vitro Mycoplasma pneumoniae Bacteroides Rubella Ureaplasma Antibacterial Antigen Bactericide Chemical element Complementary DNA DNA virus Endocarditis Genome Gram-positive bacteria Infectious disease Immune system Immunology Invertebrate Molecule Microscopy Malaria Pathogen Poliomyelitis Retrovirus Streptococcus Tuberculosis Wart Yeast Infection Encephalitis Hepatitis Antiviral drug Mold Pneumonia Diarrhea Measles Diphtheria Antiseptic Anaerobic organism Common cold Infectious mononucleosis Sepsis Anaerobic Glycoprotein Norovirus Pertussis Operon Aflatoxin Human papillomavirus Enterococcus List of human parasitic diseases Severe acute respiratory syndrome Pharyngitis Transmissible spongiform encephalopathy Erythema infectiosum Lesion Toxic shock syndrome Rheumatic fever Folliculitis Brucellosis Influenza A virus Endotoxin Disinfectant Physician assistant Epitope Pathogenesis Antifungal drug Mycotoxin Protease inhibitor (pharmacology) Cephalosporin Carbuncle Cellulitis Amphotericin B Listeriosis Nocardiosis Colitis Enterovirus Blood culture Hybridization probe Pyelonephritis Conidium Mycosis Actinomycosis Parasitic worm Leptospira Dermatophytosis Onychomycosis Nocardia Bartonellosis Sore Throat Infection control Arthroconidium Bacteroides fragilis AIDS Systemic disease Endophthalmitis Phase contrast microscopy Medical microbiology Anaplasma Dimorphic fungi Animal virology Fungi imperfecti Viral disease Hepatitis B Smallpox Mucormycosis Gonorrhea Fungus Protozoa Influenza Arthropod Nematode Coxiella Meningitis Hepatitis B virus Rubéola Médecine

Medical Microbiology
Seventh Edition

Patrick R. Murray, PhD
Worldwide Director, Scientifi c Affairs, BD Diagnostics Systems, Sparks, Maryland
Adjunct Professor, Department of Pathology, University of Maryland School of Medicine, Baltimore, Maryland

Ken S. Rosenthal, PhD
Professor, Department of Integrated Medical Sciences, Northeast Ohio Medical University, Rootstown, Ohio
Adjunct Professor, Herbert Wertheim College of Medicine, Florida International University, Miami, Florida

Michael A. Pfaller, MD
JMI Laboratories, North Liberty, Iowa
Professor Emeritus, Pathology and Epidemiology, University of Iowa College of Medicine and College of Public Health, Iowa City, Iowa
Saunders
Table of Contents
Cover image
Title page
Copyright
Dedication
Preface
Section 1: Introduction
Chapter 1: Introduction to Medical Microbiology
Viruses
Bacteria
Fungi
Parasites
Immunology
Microbial Disease
Diagnostic Microbiology
Summary
Chapter 2: Commensal and Pathogenic Microbial Flora in Humans
Respiratory Tract and Head
Gastrointestinal Tract
Genitourinary System
Skin
Chapter 3: Sterilization, Disinfection, and Antisepsis
Sterilization
Disinfection
Antisepsis
Mechanisms of Action
Section 2: General Principles of Laboratory Diagnosis
Chapter 4: Microscopy and in Vitro Culture
Microscopy
Microscopic Methods
Examination Methods
In Vitro Culture
Chapter 5: Molecular Diagnosis
Detection of Microbial Genetic Material
Detection of Proteins
Chapter 6: Serologic Diagnosis
Antibodies
Methods of Detection
Immunoassays for Cell-Associated Antigen (Immunohistology)
Immunoassays for Antibody and Soluble Antigen
Serology
Section 3: Basic Concepts in the Immune Response
Chapter 7: Elements of Host Protective Responses
Soluble Activators and Stimulators of Innate and Immune Functions
Cells of the Immune Response
Chapter 8: Innate Host Responses
Barriers to Infection
Soluble Components of Innate Responses
Cellular Components of Innate Responses
Activation of Innate Cellular Responses
Normal Flora–Associated Responses
Inflammation
Bridge to Antigen-Specific Immune Responses
Chapter 9: Antigen-Specific Immune Responses
Immunogens, Antigens, and Epitopes
T Cells
Development of T Cells
Cell Surface Receptors of T Cells
Initiation of T-Cell Responses
Activation of CD4 T Cells and Their Response to Antigen
CD8 T Cells
NKT Cells
B Cells and Humoral Immunity
Immunoglobulin Types and Structures
Immunogenetics
Antibody Response
Chapter 10: Immune Responses to Infectious Agents
Antibacterial Responses
Antiviral Responses
Specific Immune Responses to Fungi
Specific Immune Responses to Parasites
Other Immune Responses
Immunopathogenesis
Autoimmune Responses
Immunodeficiency
Chapter 11: Antimicrobial Vaccines
Types of Immunization
Immunization Programs
Section 4: Bacteriology
Chapter 12: Bacterial Classification, Structure, and Replication
Differences between Eukaryotes and Prokaryotes
Bacterial Classification
Bacterial Structure
Structure and Biosynthesis of the Major Components of the Bacterial Cell Wall
Cell Division
Spores
Chapter 13: Bacterial Metabolism and Genetics
Bacterial Metabolism
Bacterial Genes and Expression
Bacterial Genetics
Chapter 14: Mechanisms of Bacterial Pathogenesis
Entry into the Human Body
Colonization, Adhesion, and Invasion
Pathogenic Actions of Bacteria
Immunopathogenesis
Mechanisms for Escaping Host Defenses
Summary
Chapter 15: Role of Bacteria in Disease
Chapter 16: Laboratory Diagnosis of Bacterial Diseases
Specimen Collection, Transport, and Processing
Bacterial Detection and Identification
Chapter 17: Antibacterial Agents
Inhibition of Cell Wall Synthesis
Inhibition of Protein Synthesis
Inhibition of Nucleic Acid Synthesis
Other Antibiotics
Chapter 18: Staphylococcus and Related Gram-Positive Cocci
Answers
Physiology and Structure (Boxes 18-1 and 18-2)
Pathogenesis and Immunity
Epidemiology
Clinical Diseases (Box 18-3)
Laboratory Diagnosis
Treatment, Prevention, and Control
Chapter 19: Streptococcus
Answers
Streptococcus pyogenes (Box 19-1)
Streptococcus agalactiae (Box 19-3)
Other β-Hemolytic Streptococci
Viridans Streptococci
Streptococcus pneumoniae (Box 19-4)
Chapter 20: Enterococcus and Other Gram-Positive Cocci
Answers
Enterococcus (Box 20-1)
Other Catalase-Negative, Gram-Positive Cocci
Chapter 21: Bacillus
Answers
Bacillus anthracis (Box 21-1)
Bacillus cereus
Chapter 22: Listeria and Erysipelothrix
Answers
Listeria monocytogenes (Box 22-1)
Erysipelothrix rhusiopathiae (Box 22-3)
Chapter 23: Corynebacterium and Other Gram-Positive Rods
Answers
Corynebacterium diphtheriae (Box 23-1)
Other Corynebacterium Species
Other Coryneform Genera
Chapter 24: Nocardia and Related Bacteria
Answers
Nocardia (Box 24-1)
Rhodococcus
Gordonia and Tsukamurella
Chapter 25: Mycobacterium
Answers
Physiology and Structure of Mycobacteria
Mycobacterium tuberculosis (Box 25-1)
Mycobacterium leprae (Box 25-2)
Mycobacterium avium Complex (Box 25-3)
Other Slow-Growing Mycobacteria
Rapidly Growing Mycobacteria
Laboratory Diagnosis
Treatment, Prevention, and Control
Chapter 26: Neisseria and Related Genera
Answers
Neisseria gonorrhoeae and Neisseria meningitidis (Boxes 26-1 and 26-2)
Neisseria gonorrhoeae
Neisseria meningitidis
Other Neisseria Species
Eikenella corrodens
Kingella kingae
Chapter 27: Enterobacteriaceae
Answers
Physiology and Structure
Pathogenesis and Immunity
Escherichia coli (Box 27-3)
Salmonella (Box 27-4)
Shigella (Box 27-5)
Yersinia (Box 27-6)
Other Enterobacteriaceae
Laboratory Diagnosis
Treatment, Prevention, and Control
Chapter 28: Vibrio and Aeromonas
Answers
Vibrio
Aeromonas
Chapter 29: Campylobacter and Helicobacter
Answers
Campylobacter (Box 29-1)
Helicobacter (Box 29-2)
Chapter 30: Pseudomonas and Related Bacteria
Answers
Pseudomonas (Box 30-1)
Burkholderia
Stenotrophomonas maltophilia
Acinetobacter
Moraxella
Chapter 31: Haemophilus and Related Bacteria
Answers
Haemophilus (Box 31-2)
Actinobacillus
Aggregatibacter (Clinical Case 31-2)
Pasteurella (Clinical Case 31-3)
Chapter 32: Bordetella
Answers
Bordetella pertussis
Other Bordetella Species
Chapter 33: Francisella and Brucella
Answers
Francisella tularensis (Box 33-1)
Brucella (Box 33-3)
Chapter 34: Legionella
Answers
Legionellaceae
Chapter 35: Miscellaneous Gram-Negative Rods
Answers
Bartonella
Cardiobacterium
Capnocytophaga and Dysgonomonas
Streptobacillus
Chapter 36: Clostridium
Answers
Clostridium perfringens (Box 36-1)
Clostridium tetani (Box 36-3)
Clostridium botulinum (Box 36-4)
Clostridium difficile (Box 36-5)
Other Clostridial Species
Chapter 37: Anaerobic, Non–Spore-Forming, Gram-Positive Bacteria
Answers
Anaerobic Gram-Positive Cocci (Table 37-1)
Anaerobic, Non–Spore-Forming, Gram-Positive Rods (See Table 37-1)
Actinomyces
Propionibacterium
Mobiluncus
Lactobacillus
Bifidobacterium and Eubacterium
Chapter 38: Anaerobic Gram-Negative Bacteria
Answers
Physiology and Structure
Pathogenesis and Immunity
Epidemiology
Clinical Diseases
Laboratory Diagnosis
Treatment, Prevention, and Control
Chapter 39: Treponema, Borrelia, and Leptospira
Answers
Treponema (Box 39-1)
Other Treponemes
Borrelia (Box 39-3)
Leptospira (Box 39-6)
Chapter 40: Mycoplasma and Ureaplasma
Answers
Physiology and Structure
Pathogenesis and Immunity
Epidemiology
Clinical Diseases (Clinical Case 40-1)
Laboratory Diagnosis
Treatment, Prevention, and Control
Chapter 41: Rickettsia and Orientia
Answers
Physiology and Structure
Rickettsia rickettsii (Box 41-1)
Rickettsia akari
Rickettsia prowazekii (Box 41-2)
Rickettsia typhi
Orientia tsutsugamushi
Chapter 42: Ehrlichia, Anaplasma, and Coxiella
Answers
Ehrlichia and Anaplasma (Box 42-1)
Coxiella burnetii (Box 42-2)
Chapter 43: Chlamydia and Chlamydophila
Answers
Family Chlamydiaceae
Chlamydia trachomatis (Box 43-1)
Chlamydophila pneumoniae
Chlamydophila psittaci (Clinical Case 43-3)
Section 5: Virology
Chapter 44: Viral Classification, Structure, and Replication
Classification
Virion Structure
Viral Replication
Viral Genetics
Viral Vectors for Therapy
Chapter 45: Mechanisms of

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